nAChR agonist 1
CAS No. 1394371-75-5
nAChR agonist 1 ( DUN71755 )
Catalog No. M23551 CAS No. 1394371-75-5
nAChR agonist 1 is a brain-permeable and?orally?efficacious positive?allosteric? α7?nicotinic?acetylcholine?receptor (α7 nAChR)modulator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 335 | In Stock |
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10MG | 500 | In Stock |
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25MG | 806 | In Stock |
|
50MG | 1098 | In Stock |
|
100MG | 1485 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NamenAChR agonist 1
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NoteResearch use only, not for human use.
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Brief DescriptionnAChR agonist 1 is a brain-permeable and?orally?efficacious positive?allosteric? α7?nicotinic?acetylcholine?receptor (α7 nAChR)modulator.
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DescriptionnAChR agonist 1 is a brain-permeable and?orally?efficacious positive?allosteric? α7?nicotinic?acetylcholine?receptor (α7 nAChR)modulator.
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SynonymsDUN71755
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PathwayEndocrinology/Hormones
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TargetAChR
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Recptorα7 nAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number1394371-75-5
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Formula Weight420.0
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Molecular FormulaC20H18ClNO3S2
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Purity>98% (HPLC)
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SolubilityDMSO:120mg/ml(285.76mM; Need ultrasonic)
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SMILESCCC(c(sc(-c(cc1)ccc1Cl)c1C)c1-c(cc1)ccc1S(N)(=O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sinha N, et al.Discovery?of?Novel,?Potent,?Brain-Permeable, and?Orally?Efficacious?Positive?Allosteric?Modulator?of α7?Nicotinic?Acetylcholine?Receptor?[4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization. J Med Chem.?2020 Feb 13;63(3):944-960.
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