nAChR agonist 1 ( DUN71755 )

Catalog No. M23551 CAS No. 1394371-75-5

nAChR agonist 1 is a brain-permeable and?orally?efficacious positive?allosteric? α7?nicotinic?acetylcholine?receptor (α7 nAChR)modulator.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	335	In Stock
10MG	500	In Stock
25MG	806	In Stock
50MG	1098	In Stock
100MG	1485	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

nAChR agonist 1
Note

Research use only, not for human use.
Brief Description

nAChR agonist 1 is a brain-permeable and?orally?efficacious positive?allosteric? α7?nicotinic?acetylcholine?receptor (α7 nAChR)modulator.
Description

nAChR agonist 1 is a brain-permeable and?orally?efficacious positive?allosteric? α7?nicotinic?acetylcholine?receptor (α7 nAChR)modulator.
Synonyms

DUN71755
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

α7 nAChR
Research Area

——
Indication

——

Chemical Information

CAS Number

1394371-75-5
Formula Weight

420.0
Molecular Formula

C20H18ClNO3S2
Purity

>98% (HPLC)
Solubility

DMSO:120mg/ml(285.76mM; Need ultrasonic)
SMILES

CCC(c(sc(-c(cc1)ccc1Cl)c1C)c1-c(cc1)ccc1S(N)(=O)=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Sinha N, et al.Discovery?of?Novel,?Potent,?Brain-Permeable, and?Orally?Efficacious?Positive?Allosteric?Modulator?of α7?Nicotinic?Acetylcholine?Receptor?[4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization. J Med Chem.?2020 Feb 13;63(3):944-960.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks